287_63 Apr 2026

This molecule was part of a large library of triazole-modified alginates developed by researchers at MIT and Boston Children's Hospital. The goal was to find a coating that would allow implanted medical devices or encapsulated cells (like those used for Type 1 Diabetes treatment) to function inside the body without being attacked by the immune system. Key Findings for 287_63

: Highly cited papers in Nature Medicine and Nature Biotechnology (circa 2016) by the Anderson and Langer labs. 287_63

: It is a triazole-based modification of alginate, specifically created through "click chemistry" to change the surface properties of the polymer. This molecule was part of a large library

: It is a core component of U.S. Patent 10,898,443 and U.S. Patent 11,337,930 , which describe methods for making and using these modified alginates for cell therapy. ( 12 ) United States Patent - Googleapis.com : It is a triazole-based modification of alginate,